JAMS Volume 1 Issue 1

1 October 2017

The Journal of Antimicrobial Stewardship: Ready for Prime Time

Eric Wenzler, Sarah M. Wieczorkiewicz, Karri A. Bauer, Larry H. Danziger


Impact of Fosfomycin Tromethamine on the Treatment of Multi-drug Resistant Urinary Tract Infections

Ronald E. Kendall, Amy P. Hanson, Christopher W. Crank, Kamaljit S. Singh

Investigating fosfomycin use is an antimicrobial stewardship priority. With a non-resistance rate of 87.5%, it is reliable against multi-drug resistant uropathogens (MDRUs) at our institution. Fosfomycin use can decrease required duration of IV therapy, cost, and duration of hospital admission for MDRU treatment.

T2 Magnetic Resonance Assay Improves Timely Management of Candidemia

Nicole M. Wilson, George Alangaden, Robert J. Tibbetts, Linoj P. Samuel, Susan L. Davis, Rachel M. Kenney

Implementation of T2MR in conjunction with an antimicrobial stewardship program improved timely treatment of candidemia and was associated with a reduction in Candida dissemination to the eye.

visual abstract 06.05.17.jpg

Development of a Neonatal Intensive Care Unit-Specific Antibiogram: Comparison to the Hospital Antibiogram and Assessment of Patient Factors on Susceptibility

Kristen Powers, Maya Beganovic, Nicole Gockenbach, Ronda J. Oram, Sarah M. Wieczorkiewicz

A NICU-specific antibiogram may be considered to guide optimization of empiric antimicrobial therapy as susceptibilities differ compared to the overall hospital antibiogram. Patient-specific risk factors did not appear to be significantly impactful on susceptibilities in this population. 

Antimicrobial Stewardship: Widening the Collaborative Approach

Enrique Castro-Sanchez, Mark J. Gilchrist, Jo McEwen, Michelle Smith, Heather Kennedy, Alison Holmes

Antimicrobial stewardship programmes (ASPs) would benefit from the participation of nurses to strengthen the increasingly complex mix of clinical, educational, research, organisational and political interventions included within ASPs.

Implementing Antimicrobial Stewardship-Oriented Guidelines Using a Change Management Approach: The Example of Febrile Neutropenia

Miranda So, SHahid Husain, Yoshiko Nakamachi, Judy Costello, Andre C. Schuh, Marilyn Steinberg, Chaim M. Bell, Andrew M. Morris

A healthcare change management framework supported the development and implementation of a facility-specific, antimicrobial stewardship-focused clinical guideline for febrile neutropenic hematology-oncology patients. This framework may facilitate creation of local guidelines as part of the interventions of an antimicrobial stewardship program.